Journal of
Systemics, Cybernetics and Informatics
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ISSN: 1690-4524 (Online)


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Editorial Advisory Board's Chair
William Lesso

Editor-in-Chief
Nagib C. Callaos


Sponsored by
The International Institute of
Informatics and Systemics

www.iiis.org
 

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Are We Meeting Pedagogic Requirements? – The Quadratic Equation
Russell Jay Hendel
(pages: 1-7)

Facilitating Effective Student Participation in an Online Environment
Nanda van der Stap, Risa Blair
(pages: 8-11)

Virtual Global Classrooms without Walls: Collaborative Opportunities for Higher Learning Engagement
Cathy MacDonald, Debra Sheppard-LeMoine
(pages: 12-16)

Augmented Reality as Visual Communication for People with ASD
Esteban Menéndez, María Daniela López de Luise
(pages: 17-21)

Study of Race Condition: A Privilege Escalation Vulnerability
Tanjila Farah, Rashed Shelim, Moniruz Zaman, Delwar Alam
(pages: 22-26)

From the Lab to the Field: 3D Technology Supporting Study and Conservation Processes on Ancient Egyptian Artefacts
Paola Buscaglia, Elena Biondi, Alessandro Bovero, Tomasso Quirino
(pages: 27-32)

Digital Forensics Compute Cluster (DFORC2) – A New High Speed Distributed Computing Capability for Digital Forensics
Daniel Gonzales, Zev Winkelman, Trung Tran, Ricardo Sanchez, Dulani Woods, John Hollywood
(pages: 33-38)

Proposal of a Bus Location System Based on Participatory Sensing with BLE Devices and Smartphones
Katsuhiro Naito, Katsuyuki Tanaka
(pages: 39-44)

Technical Change and Employment in an Emerging Economy
Humberto Merritt
(pages: 45-53)

Interpretation of the Results of a Case Study about Impacts and Influences of Exogenous Variables in the Planning of Chronogram and Budget in Software Projects
Altino José Mentzingen de Moraes
(pages: 54-59)

Flipped Classroom – A Flexible Way of Teaching Technology Usage for Diagnostics in the Medical Subdomain ENT
Walter Koch, Jochen Schachenreiter, Klaus Vogt, Gerda Koch
(pages: 60-64)

ERP Selection: The Lifeblood of an Organization
Desmond (Tres) Bishop
(pages: 65-69)

Proposing an Education System to Judge the Necessity of Nuclear Power in Japan
Ariyoshi Kusumi
(pages: 70-74)

Biometric Encryption System for Increased Security
Ranjith Jayapal, Pramod Govindan
(pages: 75-80)

BIM as a Structural Safety Study Tool in Case of Fire - BIMSCIP
Marcelo Franco Porto, José Ricardo Queiroz Franco, Luiza Giori Barcellos Correa, Lucas Vinicius Ribeiro Alves, Renata Maria Abrantes Baracho
(pages: 81-86)

Evaluating the Construct Validity of Basic Science Curriculum Assessment Instrument for Critical Thinking: A Case-Study
Chau-Kuang Chen, Adriana Marie Horner, Michelle Scott, Stephanie C. McClure
(pages: 87-92)

The Outer Banks Study – Physio-Chemical Parameters for Water Quality Testing/Professional Development Program for Teachers
Joseph Stringer, Timothy Bowman, Keith Vinson, Catherine Warnecke, Nora Lewis, William Slattery, Suzanne K. Lunsford
(pages: 93-97)


 

Abstracts

 


ABSTRACT


Deformation of Cell Passing through Micro Slit between Micro Ridges Fabricated by Photolithography Technique

Yusuke Takahashi, Shigehiro Hashimoto, Atsushi Mizoi, Haruka Hino


A micro slit has been designed between micro ridges, and deformation of a biological cell passing through the micro slit has been observed in vitro. The slit, of which the width is 0.87 mm and the height is 0.010 mm, has been made between the micro ridges on the transparent polydimethylsiloxane disk and on the glass disk by the photolithography technique. The slit is placed at the middle part of a flow channel. Four kinds of cells were used in the experiment: C2C12 (mouse myoblast cells), HUVEC (human umbilical vein endothelial cells), Hepa1-6 (mouse hepatoma cells), and Neuro-2a (mouse neural crest-derived cells). The suspension of each kind of cells was introduced to the slits. The deformation of cells passing through the micro slit was observed with an inverted phase-contrast microscope. The experimental results show that cells deform to the flat circular disk and pass through the micro slit of 0.010 mm height. The deformation ratio, the passing velocity, and the shape index of cells through the slit were evaluated: Hepa1-6 is deformed with the increase of the passing velocity, and HUVEC elongates along the flow. The designed slit between micro ridges has capability to evaluate the deformability of cells.

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