This article defines learning as the gap between current and required knowledge and teaching as the process of designing and implementing interventions to reduce that gap. It then lists principles for good learning to occur. These principles require that interventions be designed with multiple disciplines in mind so that the student is able, capable, and willing to learn the intended subject matter. It then lists the constraints to applying these principles in the lecture, online, and blended modalities. It concludes by defining a rigorous teaching process as one that follows the principles of continual improvement as defined by Deming’s PDSA cycle.