Cell Sorting Using Diagonal Bottom Grooves in a Microchannel
Kota Yamamoto, Shigehiro Hashimoto
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Kota Yamamoto
Biomedical Engineering, Department of Mechanical Engineering, Kogakunin University, Tokyo, Japan
Shigehiro Hashimoto
Biomedical Engineering, Department of Mechanical Engineering, Kogakunin University, Tokyo, Japan
Cite this paper as:Yamamoto, K., Hashimoto, S. (2024). Cell Sorting Using Diagonal Bottom Grooves in a Microchannel.
Journal of Systemics, Cybernetics and Informatics, 22(2), 48-53. https://doi.org/10.54808/JSCI.22.02.48
Online ISSN (Journal): 1690-4524
Abstract
Cell shape is related to cell function. For the purpose of cell sorting based on shape, a channel with diagonal grooves on the bottom was designed. A cell suspension was poured into a channel created by micromachining, and cell sorting according to shape was confirmed. Experimental results shows that smaller and more elongated cells undergo a larger shift perpendicular to the mainstream direction during passing over the groove. Diagonal bottom grooves in a microchannel are effective for cell sorting.
