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A Transdisciplinary Approach to Enhancing Online Engineering Education Through Learning Analytics Masikini Lugoma , Lethuxolo Yende , Pule Dikgwatlhe , Akhona Mkonde , Rorisang Thage , Lucky Maseko , Ngonidzashe Chimwani (pages: 1-6) AI Disruptions in Higher Education: Evolutionary Change, Not Revolutionary Overthrow Cristo Leon , James Lipuma , Maximus Rafla (pages: 7-18) Education, Research, and Methodology: A Transdisciplinary Cybernetic Whole Nagib Callaos , Cristo Leon (pages: 19-33) Enhancing Educational Effectiveness Through Transdisciplinary Practice: The ETCOP Model Birgit Oberer , Alptekin Erkollar , Andreas Kropfberger (pages: 34-40) From Instruction to Interaction: Reflexive Learning Design for Cross-Generational Engagement at the Workplace Gita Aulia Nurani , Ya-Hui Lee (pages: 41-44) GIS in Aquatic Animal Health Surveillance: A Transdisciplinary eLearning Initiative Integrating Education, Research, and Methodology (The Aquae Strength Project) Eleonora Franzago , Rodrigo Macario , Matteo Mazzucato , Federica Sbettega , Manuela Cassani , Guido Ricaldi , Francesco Bissoli , Anna Nadin , Fabrizio Personeni , Manuela Dalla Pozza , Grazia Manca , Nicola Ferré (pages: 45-50) Reflexivity as a Compass: The European AI Act and Its Implications for U.S. Higher Education Institutions Jasmin Cowin (pages: 51-56) Required General Education Program Evaluation: Bridging the Gap Between Educators and Administrators James Lipuma , Cristo Leon , Jeremy Reich (pages: 57-61) Researching Ourselves Jeremy Horne (pages: 62-72) The Self-Aware, Reflective Learner: Fostering Metacognitive Awareness and Reflexivity in Undergraduates Through Service-Learning Genejane Adarlo (pages: 73-81)
ABSTRACT
Semiparametric Mixed Effect Model with Application to the Longitudinal Knee
Osteoarthritis (OAK) Data
Motivated by the study of the longitudinal development and
progression of knee osteoarthritis (OA) over a 15-year period,
this study developed non-parametric mixed-effect models for
ordinal outcomes. A stochastic mixed-effect model was used to
evaluate the similarity of trajectories associated with increasing
disease severity of OA in both knees. Then, a non-parametric
mixed-effects model, based on cubic B-splnes, was developed
to characterize the unknown nonlinear trend of logits as a
function of time1-order. A Markov Transition Model was
developed to characterize the transitions among multi-states of
knee OA. This newly developed approach allows more flexible
functional dependence of the ordinal outcome, levels of
increasing knee OA severity, on the covariates.
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