Journal of
Systemics, Cybernetics and Informatics
 



ISSN: 1690-4524 (Online)


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Honorary Editorial Advisory Board's Chair
William Lesso (1931-2015)

Editor-in-Chief
Nagib C. Callaos


Sponsored by
The International Institute of
Informatics and Systemics

www.iiis.org
 

Editorial Advisory Board

Editors

Journal's Reviewers
 

Description and Aims

Submission of Articles

Areas and Subareas

Information to Contributors

Editorial Peer Review Methodology

Integrating Reviewing Processes


A Systemic/Cybernetic Notion of Design
Nagib Callaos
(pages: 1-29)

The Philosophy of Research
Jeremy Horne
(pages: 30-56)

On Architecture: Complexity and Decline
Taha A. Al-Douri
(pages: 57-61)

The Humboldt Portal: Complexity and Interconnectedness
Detlev Doherr
(pages: 62-71)

The Influence of Tradition, Context, and Research in Doctoral Degree Design
Lorayne Robertson, Bill Muirhead
(pages: 72-82)

Viability, Sustainability and Non-Requisite Variety
Leonardo Lavanderos, Abelardo Araya, Alejandro Malpartida
(pages: 83-96)

Increase the Success of Governmental IT-Projects
Maurice Gaikema, Mark Donkersloot, Jim Johnson, Hans Mulder
(pages: 97-105)

The Interconnections of Research and Design in Context of Social Trust and the Triple Helix Concept
Annamaria Csiszer
(pages: 106-116)

Problems During Scientific Research and Designing Integration
Ingus Mitrofanovs, Marita Cekule, Kaspars Cabs
(pages: 117-128)

Current State and Modeling of Research Topics in Cybersecurity and Data Science
Tamir Bechor, Bill Jung
(pages: 129-156)

Transforming Cybersecurity Education Through Consulting
Giti Javidi, Ehsan Sheybani
(pages: 157-168)

Designing for Learning in an Interdisciplinary Education Context
Lillian Buus, Jette A. Frydendahl, Thomas W. Jensen, Thue F. Jensen, Kirstine B. Lillelund, Mette Falbe-Hansen
(pages: 169-185)

Analysis of Information in the Academic Management of the UNED, Required in the Self-Assessment Processes and the Relation Between Research and Design of the Investigation
Ariana Acón-Matamoros, Aurora Trujillo-Cotera
(pages: 186-196)

Designing a Supply System for a Productive Company
Javier Chávez González, Graciela Vázquez Álvarez, Efraín J. Martínez Ortíz, Sandra D. Orantes Jiménez
(pages: 197-212)

A Novel Interactive Network Fuzzer for System Security Assessment
Jaime C. Acosta, Christian Murga, Alberto Morales, Caesar Zapata
(pages: 213-220)

Designing for Proactive Network Configuration Analysis
Magreth Mushi, Rudra Dutta
(pages: 221-239)

Research Design for Evaluating the Impact in SMES Related to the Technological Means Imposed by the Mexican Tax Authorities
Jesús Vivanco, Ma. del Carmen Martinez
(pages: 240-248)

Evaluation by Competences in a Clinical Environment of a Public University in Peru (Invited Paper)
Maritza Placencia Medina, Javier Silva Valencia, Elías J. Carrasco Escobedo, Marissa Muñoz-Ayala, Jorge R. Carreño Escobedo, Carlos Saavedra Castillo, Yanelli K. Ascacivar Placencia
(pages: 249-259)

Development of the Software Cryptographic Service Provider on the Basis of National Standards
Rakhmatillo Djuraevich Aloev, Mirkhon Mukhammadovich Nurullaev
(pages: 260-272)

On the Calculation of Entropy of EEG Transients
Carlos A. Ramírez-Fuentes, Blanca Tovar-Corona, V. Barrera-Figueroa, M. A. Silva-Ramírez, L. I. Garay-Jiménez
(pages: 273-286)

The Legitimization of Improvement Science in Academe
Casey D. Cobb, Patricia Virella
(pages: 287-296)


 

Abstracts

 


ABSTRACT


Functional Magnetic Resonance Imaging of Goal-Directed Reaching in Children with Autism Spectrum Disorders: A Feasibility Study

Nicole M. G. Salowitz, Bridget Dolan, Rheanna Remmel, Amy Vaughan Van Hecke, Kristine Mosier, Lucia Simo, Robert A. Scheidt


An unanswered question concerning the neural basis of autism spectrum disorders (ASD) is how sensorimotor deficits in individuals with ASD are related to abnormalities of brain function. We previously described a robotic joystick and video game system that allows us to record functional magnetic resonance images (FMRI) while adult humans make goal-directed wrist motions. We anticipated several challenges in extending this approach to studying goal-directed behaviors in children with ASD and in typically developing (TYP) children. In particular we were concerned that children with autism may express increased levels of anxiety as compared to typically developing children due to the loud sounds and small enclosed space of the MRI scanner. We also were concerned that both groups of children might become restless during testing, leading to an unacceptable amount of head movement. Here we performed a pilot study evaluating the extent to which autistic and typically developing children exhibit anxiety during our experimental protocol as well as their ability to comply with task instructions. Our experimental controls were successful in minimizing group differences in drop-out due to anxiety. Kinematic performance and head motion also were similar across groups. Both groups of children engaged cortical regions (frontal, parietal, temporal, occipital) while making goal-directed movements. In addition, the ASD group exhibited task-related correlations in subcortical regions (cerebellum, thalamus), whereas correlations in the TYP group did not reach statistical significance in subcortical regions. Four distinct regions in frontal cortex showed a significant group difference such that TYP children exhibited positive correlations between the hemodynamic response and movement, whereas children with ASD exhibited negative correlations. These findings demonstrate feasibility of simultaneous application of robotic manipulation and functional imaging to study goal-directed motor behaviors in autistic and typically developing children. The findings also suggest the presence of marked changes in neural activation during a sensorimotor task requiring goal-directed movement.

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